What Is PT-141?
PT-141 (Bremelanotide) is a cyclic heptapeptide metabolite of Melanotan II, formed via removal of the C-terminal amide group. It acts as a melanocortin receptor agonist with preferential activity at MC3R and MC4R over MC1R — distinguishing it from its parent compound's non-selective receptor profile. This selectivity is the primary research rationale for using PT-141 over Melanotan II when studying MC3R or MC4R-driven pathways in isolation.
Preclinical research has examined PT-141 in sexual function models (MC4R), appetite and energy homeostasis (MC3R/MC4R), and inflammatory response pathways. The reduced MC1R activity means melanogenesis is a less confounding variable in MC3R/MC4R research designs. Eternal Peptides Wholesale stocks both PT-141 (PT10) and Melanotan II (MT10) for comparative receptor research.
For non-selective melanocortin receptor research, see Melanotan II (MT10). For research use only.
PT-141 Products
Supplied as lyophilised powder in boxes of 10 research-grade vials.
Frequently Asked Questions
Where can I buy PT-141 in Australia? +
Eternal Peptides Wholesale is an Australian-owned, online distributor supplying PT-141 for research purposes. PT10 (10mg, box of 10) is $544.50. Kovera Labs reports, Free shipping. For research use only.
How does PT-141 differ from Melanotan II? +
MT-II activates MC1R, MC3R, MC4R, and MC5R. PT-141 is its metabolite with reduced MC1R affinity, enabling more selective MC3R/MC4R research with less confounding melanogenesis. Both are available from Eternal Peptides Wholesale. See the Melanotan II page. For research use only.
How is PT-141 quality verified? +
Each product page publishes the Kovera Labs reports for its batch. Each report lists the method, stated criterion and result for its batch.
How quickly is PT10 dispatched? +
Consult our Shipping Policy for processing and delivery estimates. Dispatch origin can vary, including offshore fulfilment; Australian business ownership does not guarantee domestic stock or customs-free delivery. Kovera Labs purity, endotoxin, heavy-metal and sterility reports are published on each product page.
Related Research Resources
Research and buying guide
Testing references updated 1 November 2026 for the published Kovera Labs report set. Original research and catalogue snapshot dates remain as stated.
Kovera Labs testing: purity, endotoxin, heavy metals and sterility
Our listed batches are tested by Kovera Labs, and the reports are published on each product page: HPLC purity and LC-MS identity, endotoxin (EU/mL), heavy metals (lead, arsenic, cadmium and mercury) and sterility (bacteria and fungi), each with a batch number, report ID and a link to the laboratory’s verification record.
- PT-141 (10mg) – batch EP-260524-PT10: HPLC purity 99.262% and LC-MS identity COA · COA library entry
How we test: purity, endotoxin, heavy metals and sterility · Kovera Labs COA library · Eternal Peptides Wholesale
For laboratory research use only.